Effect of chorionic villus sampling on uterine artery Doppler.
نویسندگان
چکیده
INTRODUCTION The aim of this study was to examine the potential effect of chorionic villus sampling (CVS) on placental perfusion by examining the change in uterine artery pulsatility index (PI) between the first and second trimesters of pregnancy. MATERIALS AND METHODS This was a prospective screening study for pregnancy complications which included measurement of uterine artery PI at 11(+0) to 13(+6) weeks and at 20(+0) to 24(+6) weeks of gestation. In women at increased risk for fetal aneuploidies, CVS was performed. Uterine artery PI in the first and second trimesters, and the change in PI between the two examinations were compared between the CVS and non-CVS groups. RESULTS The study population included 8,822 singleton pregnancies, in 308 of which CVS was performed. In the CVS group, compared to the non-CVS group, the median uterine artery PI before CVS, corrected for gestational age, was higher in both the first and second trimesters of pregnancy, but the change in PI between the two examinations was not significantly different (p = 0.789). CONCLUSION The performance of CVS in the first trimester is unlikely to interfere with normal placentation.
منابع مشابه
Uterine artery Doppler velocimetry , calcium and lipids in pregnant women of advanced age
Women of advanced maternal age are considered to be at a substantially increased risk of spontaneous abortion. The increased spontaneous abortion rate in older women rnight be associated with a defective vascular response to placentation, which rnight lead to fetal ischaemia and fetal dead. Doppler velocirnetry of the uterine artery allows non-invasive assessment of uteroplacental hemodynamics....
متن کاملUterine artery Doppler at 11-14 weeks of gestation in chromosomally abnormal fetuses.
OBJECTIVE To determine whether the major chromosomal abnormalities are associated with impaired placentation in the first trimester of pregnancy. METHODS This was a prospective study of 692 singleton pregnancies undergoing fetal karyotyping at 11-14 weeks of gestation. Uterine artery Doppler was carried out and the mean pulsatility index was calculated just before chorionic villus sampling. ...
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Background: To evaluate the effect of oxytocin on blood circulation of fetus and uterus by Doppler ultrasound. Materials and Methods: Forty six pregnant women were assigned to receive for indication of delivery intravenous oxytocin. Doppler velocitometry before and after administration of oxytocin for umbilical,middle cerebral artery and uterine artery were performed, and Pulsatility index (PI)...
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Background: Chorionic villus sampling refers to a procedure in which small samples of placenta are obtained for prenatal genetic diagnosis, generally in the first trimester of pregnancy in 11 weeks till 13 weeks+6 days. This procedure provides prenatal diagnosis in pregnancy. Amniocentesis is a technique for windrowing amniotic fluid from the uterine cavity using a needle via a trans abdominal ...
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ورودعنوان ژورنال:
- Fetal diagnosis and therapy
دوره 28 1 شماره
صفحات -
تاریخ انتشار 2010